|
Selenium
Research :
Articles on research, clinical trials, analysis,
reviews and empirical studies
Much
of the research cited herein will be found on PubMed, a
service of the National Library of Medicine. PubMed includes
over 15 million citations from MEDLINE and other life science
journals for biomedical articles back to the 1950s. PubMed
includes links to full text articles and other related resources.
Click
on the author's name to view the abstract
Boosting the Immune System
Host
nutritional selenium status as a driving force for influenza
virus mutations (PDF file)
Heather K. Nelson, Qing Shi, Peter Van Dael, Eduardo J.
Schiffrin, Stephanie Blum, Denis Barclay, Orville A. Levander,
and Melinda A. Beck, Departments of Nutrition and Pediatrics,
University of NC at Chapel Hill; Nestlé Research
Center, Lausanne, Switzerland; and USDA, ARS, Beltsville
Human Nutrition Research Center, Beltsville, MD Corresponding
author: Melinda A. Beck, Ph.D., Department of Pediatrics,
535 Burnett-Womack, CB #7220, University of North Carolina
at Chapel Hill
Se-adequate mice infected with virus recovered from Se-deficient
mice develop severe lung pathology Previous work in our
laboratory (5) demonstrated that Se-deficient mice developed
much more severe pathology postinfluenza virus infection
than did Se-adequate mice.
Broome
CS, McArdle F, Kyle JA, Andrews F, Lowe NM, Hart CA, Arthur
JR, Jackson MJ. An increase in selenium intake improves
immune function and poliovirus handling in adults with marginal
selenium status. Am J Clin Nutr. 2004 Jul;80(1):154-62.
McCarty MF. natural antimutagenic agents may prolong
efficacy of human immunodeficiency virus drug therapy. Med
Hypotheses. 1997 Mar;48(3):215-20.
Beck MA, Shi Q, Morris VC, Levander OA. Rapid genomic
evolution of a non-virulent coxsackievirus B3 in selenium-deficient
mice results in selection of identical virulent isolates.
Nat Med. 1995 May;1(5):433-6.
Kiremidjian-Schumacher L, Roy M, Wishe HI, Cohen MW, Stotzky
G. Supplementation with selenium and human immune cell
functions. II. Effect on cytotoxic lymphocytes and natural
killer cells.
Biol Trace Elem Res. 1994 Apr-May;41(1-2):115-27.
Burbano X, Miguez-Burbano MJ, McCollister K, Zhang G, Rodriguez
A, Ruiz P, Lecusay R, Shor-Posner G. Impact of a selenium
chemoprevention clinical trial on hospital admissions of
HIV-infected participants. HIV Clin Trials. 2002 Nov-Dec;3(6):483-91.
Baum MK, Shor-Posner G, Lai S, Zhang G, Lai H, Fletcher
MA, Sauberlich H, Page JB. High risk of HIV-related
mortality is associated with selenium deficiency. J Acquir
Immune Defic Syndr Hum Retrovirol. 1997 Aug 15;15(5):370-4.
Preventing Cancer
El-Bayoumy K. The protective role of selenium on genetic
damage and on cancer. Mutat Res. 2001 Apr 18;475(1-2):123-39.
Combs GF Jr. Status of selenium in prostate cancer prevention.
Br J Cancer. 2004 Jul 19;91(2):195-9.
Mantovani G, Maccio A, Madeddu C, Serpe R, Massa E, Gramignano
G, Lusso MR, Curreli N, Rinaldi A. Selenium is effective
in inducing lymphocyte progression through cell cycle in
cancer patients: potential mechanisms for its activity.
J Exp Ther Oncol. 2004 Apr;4(1):69-78.
Sieja K, Talerczyk M. Selenium as an element in the
treatment of ovarian cancer in women receiving chemotherapy.
Gynecol Oncol. 2004 May;93(2):320-7.
Finley JW. Reduction of cancer risk by consumption of
selenium-enriched plants: enrichment of broccoli with selenium
increases the anticarcinogenic properties of broccoli. J
Med Food. 2003 Spring;6(1):19-26.
Zeegers MP, Goldbohm RA, Bode P, van den Brandt PA.
Prediagnostic toenail selenium and risk of bladder cancer.
Cancer Epidemiol Biomarkers Prev. 2002 Nov;11(11):1292-7.
Yadav SP, Gera A, Singh I, Chanda R. Serum selenium
levels in patients with head and neck cancer.
J Otolaryngol. 2002 Aug;31(4):216-9.
Combs GF Jr. Impact of selenium and cancer-prevention
findings on the nutrition-health paradigm.
Nutr Cancer. 2001;40(1):6-11.
Detoxification of Heavy Metals
Patrick L. Toxic metals and antioxidants: Part II. The
role of antioxidants in arsenic and cadmium toxicity. Altern
Med Rev. 2003 May;8(2):106-28.
Whanger PD. Selenium in the treatment of heavy metal
poisoning and chemical carcinogenesis.
J Trace Elem Electrolytes Health Dis. 1992 Dec;6(4):209-21.
Yoshinaga J, Matsuo N, Imai H, Nakazawa M, Suzuki T, Morita
M, Akagi H. Interrelationship between the concentrations
of some elements in the organs of Japanese with special
reference to selenium-heavy metal relationships. Sci Total
Environ. 1990 Feb;91:127-40.
Nuttall KL. A model for metal selenide formation under
biological conditions. Med Hypotheses. 1987 Oct;24(2):217-21.
Schrauzer GN. Effects of selenium antagonists on cancer
susceptibility: new aspects of chronic heavy metal toxicity.
J UOEH. 1987 Mar 20;9 Suppl:208-15.
Chowdhury BA, Chandra RK. Biological and health implications
of toxic heavy metal and essential trace element interactions.
Prog Food Nutr Sci. 1987;11(1):55-113.
Thyroid
Kohrle J. The trace element selenium and the thyroid
gland. Biochimie. 1999 May;81(5):527-33.
Sher L. Role of thyroid hormones in the effects of selenium
on mood, behavior, and cognitive function.
Med Hypotheses. 2001 Oct;57(4):480-3. Br J Urol. 1998 Jul;82(1):76-80.
Gartner R, Gasnier BC, Dietrich JW, Krebs B, Angstwurm MW.
Selenium supplementation in patients with autoimmune thyroiditis
decreases thyroid peroxidase antibodies concentrations.
J Clin Endocrinol Metab. 2002 Apr;87(4):1687-91.
Other Uses
Scott R, MacPherson A, Yates RW, Hussain B, Dixon J.
The effect of oral selenium supplementation on human sperm
motility. Br J Urol. 1998 Jul;82(1):76-80.
|
